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Chromatin-associated protein SIN3B prevents prostate cancer progression by inducing senescence

Distinguishing between indolent and aggressive prostate adenocarcinoma (PCa) remains a priority to accurately identify patients who need therapeutic intervention. SIN3B has been implicated in the initiation of senescence in vitro. Here we show that in a mouse model of prostate cancer, SIN3B provides...

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Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: Bainor, Anthony J., Deng, Fang-Ming, Wang, Yu, Lee, Peng, Cantor, David J., Logan, Susan K., David, Gregory
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626631/
https://ncbi.nlm.nih.gov/pubmed/28807943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3410
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