Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate‐activated protein kinase‐related kinases and retinoid X receptor α

Ribavirin (RBV) has been widely used as an antiviral reagent, specifically for patients with chronic hepatitis C. We previously demonstrated that adenosine kinase, which monophosphorylates RBV into the metabolically active form, is a key determinant for RBV sensitivity against hepatitis C virus RNA...

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書目詳細資料
發表在:Hepatol Commun
Main Authors: Satoh, Shinya, Mori, Kyoko, Onomura, Daichi, Ueda, Youki, Dansako, Hiromichi, Honda, Masao, Kaneko, Shuichi, Ikeda, Masanori, Kato, Nobuyuki
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678905/
https://ncbi.nlm.nih.gov/pubmed/29404478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1065
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