Establishment of Hepatitis C Virus RNA-Replicating Cell Lines Possessing Ribavirin-Resistant Phenotype

BACKGROUND: Ribavirin (RBV) is a potential partner of interferon-based therapy and recently approved therapy using direct acting antivirals for patients with chronic hepatitis C. However, the precise mechanisms underlying RBV action against hepatitis C virus (HCV) replication are not yet understood....

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Veröffentlicht in:PLoS One
Hauptverfasser: Satoh, Shinya, Mori, Kyoko, Ueda, Youki, Sejima, Hiroe, Dansako, Hiromichi, Ikeda, Masanori, Kato, Nobuyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336140/
https://ncbi.nlm.nih.gov/pubmed/25699517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118313
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