Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate‐activated protein kinase‐related kinases and retinoid X receptor α

Ribavirin (RBV) has been widely used as an antiviral reagent, specifically for patients with chronic hepatitis C. We previously demonstrated that adenosine kinase, which monophosphorylates RBV into the metabolically active form, is a key determinant for RBV sensitivity against hepatitis C virus RNA...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Hepatol Commun
Κύριοι συγγραφείς: Satoh, Shinya, Mori, Kyoko, Onomura, Daichi, Ueda, Youki, Dansako, Hiromichi, Honda, Masao, Kaneko, Shuichi, Ikeda, Masanori, Kato, Nobuyuki
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2017
Θέματα:
Original Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678905/
https://ncbi.nlm.nih.gov/pubmed/29404478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1065
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