Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate‐activated protein kinase‐related kinases and retinoid X receptor α

Ribavirin (RBV) has been widely used as an antiviral reagent, specifically for patients with chronic hepatitis C. We previously demonstrated that adenosine kinase, which monophosphorylates RBV into the metabolically active form, is a key determinant for RBV sensitivity against hepatitis C virus RNA...

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Dades bibliogràfiques
Publicat a:Hepatol Commun
Autors principals: Satoh, Shinya, Mori, Kyoko, Onomura, Daichi, Ueda, Youki, Dansako, Hiromichi, Honda, Masao, Kaneko, Shuichi, Ikeda, Masanori, Kato, Nobuyuki
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678905/
https://ncbi.nlm.nih.gov/pubmed/29404478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1065
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