High‐level expression of STING restricts susceptibility to HBV by mediating type III IFN induction

Hepatitis B virus (HBV) is a hepatotropic DNA virus causing hepatic diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. To study HBV, human hepatoma HepG2 cells are currently used as an HBV infectious cell culture model worldwide. HepG2 cells exhibit susceptibility to...

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Bibliographic Details
Published in:FASEB Bioadv
Main Authors: Dansako, Hiromichi, Imai, Hirotaka, Ueda, Youki, Satoh, Shinya, Shimotohno, Kunitada, Kato, Nobuyuki
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996391/
https://ncbi.nlm.nih.gov/pubmed/32123822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.1022
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