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Ethanol‐induced steatosis involves impairment of lipophagy, associated with reduced Dynamin2 activity

Lipid droplets (LDs), the organelles central to alcoholic steatosis, are broken down by lipophagy, a specialized form of autophagy. Here, we hypothesize that ethanol administration retards lipophagy by down‐regulating dynamin 2 (Dyn2), a protein that facilitates lysosome re‐formation, contributing t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hepatol Commun
Egile Nagusiak: Rasineni, Karuna, Donohue, Terrence M., Thomes, Paul G., Yang, Li, Tuma, Dean J., McNiven, Mark A., Casey, Carol A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678901/
https://ncbi.nlm.nih.gov/pubmed/29152606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1063
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