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Ethanol exposure inhibits hepatocyte lipophagy by inactivating the small guanosine triphosphatase Rab7

Alcohol consumption is a well‐established risk factor for the onset and progression of fatty liver disease. An estimated 90% of heavy drinkers are thought to develop significant liver steatosis. For these reasons, an increased understanding of the molecular basis for alcohol‐induced hepatic steatosi...

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Vydáno v:Hepatol Commun
Hlavní autoři: Schulze, Ryan J., Rasineni, Karuna, Weller, Shaun G., Schott, Micah B., Schroeder, Barbara, Casey, Carol A., McNiven, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721426/
https://ncbi.nlm.nih.gov/pubmed/29404450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1021
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