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Ethanol‐induced steatosis involves impairment of lipophagy, associated with reduced Dynamin2 activity
Lipid droplets (LDs), the organelles central to alcoholic steatosis, are broken down by lipophagy, a specialized form of autophagy. Here, we hypothesize that ethanol administration retards lipophagy by down‐regulating dynamin 2 (Dyn2), a protein that facilitates lysosome re‐formation, contributing t...
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| 發表在: | Hepatol Commun |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5678901/ https://ncbi.nlm.nih.gov/pubmed/29152606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1063 |
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