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Clusterin protects neurons against intracellular proteotoxicity

It is now widely accepted in the field that the normally secreted chaperone clusterin is redirected to the cytosol during endoplasmic reticulum (ER) stress, although the physiological function(s) of this physical relocation remain unknown. We have examined in this study whether or not increased expr...

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Bibliografske podrobnosti
izdano v:Acta Neuropathol Commun
Main Authors: Gregory, Jenna M., Whiten, Daniel R., Brown, Rebecca A., Barros, Teresa P., Kumita, Janet R., Yerbury, Justin J., Satapathy, Sandeep, McDade, Karina, Smith, Colin, Luheshi, Leila M., Dobson, Christopher M., Wilson, Mark R.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678579/
https://ncbi.nlm.nih.gov/pubmed/29115989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0481-1
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