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The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease involving the formation of cytoplasmic aggregates by proteins including TDP-43 and SOD1, in affected cells in the central nervous system (CNS). Pathology spreads from an initial site of onset to contiguous anatomical regions. There i...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Basis Dis
Main Authors: Hanspal, Maya A., Dobson, Christopher M., Yerbury, Justin J., Kumita, Janet R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565888/
https://ncbi.nlm.nih.gov/pubmed/28711596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.07.007
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