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Structural Characterization of Clusterin-Chaperone Client Protein Complexes

Clusterin (CLU) is a potent extracellular chaperone that inhibits protein aggregation and precipitation otherwise caused by physical or chemical stresses (e.g. heat, reduction). This action involves CLU forming soluble high molecular weight (HMW) complexes with the client protein. Other than their u...

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Bibliografiska uppgifter
Huvudupphovsmän: Wyatt, Amy R., Yerbury, Justin J., Wilson, Mark R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755916/
https://ncbi.nlm.nih.gov/pubmed/19535339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033688
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