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Structural Characterization of Clusterin-Chaperone Client Protein Complexes

Clusterin (CLU) is a potent extracellular chaperone that inhibits protein aggregation and precipitation otherwise caused by physical or chemical stresses (e.g. heat, reduction). This action involves CLU forming soluble high molecular weight (HMW) complexes with the client protein. Other than their u...

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Detalhes bibliográficos
Main Authors: Wyatt, Amy R., Yerbury, Justin J., Wilson, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755916/
https://ncbi.nlm.nih.gov/pubmed/19535339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033688
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