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Rapid high-yield expression and purification of fully post-translationally modified recombinant clusterin and mutants

The first described and best known mammalian secreted chaperone, abundant in human blood, is clusterin. Recent independent studies are now exploring the potential use of clusterin as a therapeutic in a variety of disease contexts. In the past, the extensive post-translational processing of clusterin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Satapathy, Sandeep, Dabbs, Rebecca A., Wilson, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455699/
https://ncbi.nlm.nih.gov/pubmed/32859921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70990-3
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