Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation

Although efficacy of combined histone deacetylase (HDAC) inhibitors and conventional photon radiotherapy is being tested in clinical trials, their combined effect with proton beam radiotherapy has yet to be determined. Here, we compared combined effect of valproic acid (VPA), a class I and II HDAC i...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Yu, Jeong Il, Choi, Changhoon, Shin, Sung-Won, Son, Arang, Lee, Ga-Haeng, Kim, Shin-Yeong, Park, Hee Chul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678087/
https://ncbi.nlm.nih.gov/pubmed/29118323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15165-3
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