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Downregulation of Mcl-1 by Panobinostat Potentiates Proton Beam Therapy in Hepatocellular Carcinoma Cells

Epigenetic modulation by histone deacetylase (HDAC) inhibitors is an attractive anti-cancer strategy for diverse hematological and solid cancers. Herein, we explored the relative effectiveness of the pan-HDAC inhibitor panobinostat in combination with proton over X-ray irradiation in HCC cells. Clon...

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Detalhes bibliográficos
Publicado no:Cells
Principais autores: Choi, Changhoon, Lee, Ga Haeng, Son, Arang, Yoo, Gyu Sang, Yu, Jeong Il, Park, Hee Chul
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999709/
https://ncbi.nlm.nih.gov/pubmed/33806487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030554
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