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Workflow optimization of whole genome amplification and targeted panel sequencing for CTC mutation detection
Genomic characterization of circulating tumor cells (CTCs) may prove useful as a surrogate for conventional tissue biopsies. This is particularly important as studies have shown different mutational profiles between CTCs and ctDNA in some tumor subtypes. However, isolating rare CTCs from whole blood...
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| Publicado no: | NPJ Genom Med |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5677973/ https://ncbi.nlm.nih.gov/pubmed/29263843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-017-0034-3 |
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