Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer

Treatment of advanced colorectal cancer (CRC) requires multimodal therapeutic approaches and need for monitoring tumor plasticity. Liquid biopsy biomarkers, including CTCs and ctDNA, hold promise for evaluating treatment response in real-time and guiding therapeutic modifications. From 15 patients w...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kidess-Sigal, Evelyn, Liu, Haiyan E., Triboulet, Melanie M., Che, James, Ramani, Vishnu C., Visser, Brendan C., Poultsides, George A., Longacre, Teri A., Marziali, Andre, Vysotskaia, Valentina, Wiggin, Matthew, Heirich, Kyra, Hanft, Violet, Keilholz, Ulrich, Tinhofer, Ingeborg, Norton, Jeffrey A., Lee, Mark, Sollier-Christen, Elodie, Jeffrey, Stefanie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356741/
https://ncbi.nlm.nih.gov/pubmed/27863403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13350
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