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Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123

Kap123, a major karyopherin protein of budding yeast, recognizes the nuclear localization signals (NLSs) of cytoplasmic histones H3 and H4 and translocates them into the nucleus during DNA replication. Mechanistic questions include H3- and H4-NLS redundancy toward Kap123 and the role of the conserve...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: An, Sojin, Yoon, Jungmin, Kim, Hanseong, Song, Ji-Joon, Cho, Uhn-soo
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677370/
https://ncbi.nlm.nih.gov/pubmed/29035199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30244
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