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Evidence for the nuclear import of histones H3.1 and H4 as monomers
Newly synthesised histones are thought to dimerise in the cytosol and undergo nuclear import in complex with histone chaperones. Here, we provide evidence that human H3.1 and H4 are imported into the nucleus as monomers. Using a tether‐and‐release system to study the import dynamics of newly synthes...
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| Udgivet i: | EMBO J |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6166134/ https://ncbi.nlm.nih.gov/pubmed/30177573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798714 |
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