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Evidence for the nuclear import of histones H3.1 and H4 as monomers

Newly synthesised histones are thought to dimerise in the cytosol and undergo nuclear import in complex with histone chaperones. Here, we provide evidence that human H3.1 and H4 are imported into the nucleus as monomers. Using a tether‐and‐release system to study the import dynamics of newly synthes...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Apta‐Smith, Michael James, Hernandez‐Fernaud, Juan Ramon, Bowman, Andrew James
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166134/
https://ncbi.nlm.nih.gov/pubmed/30177573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798714
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