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Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123
Kap123, a major karyopherin protein of budding yeast, recognizes the nuclear localization signals (NLSs) of cytoplasmic histones H3 and H4 and translocates them into the nucleus during DNA replication. Mechanistic questions include H3- and H4-NLS redundancy toward Kap123 and the role of the conserve...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5677370/ https://ncbi.nlm.nih.gov/pubmed/29035199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30244 |
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