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Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone
We report the crystal structure of nuclear import receptor Importin-9 bound to its cargo, the histones H2A-H2B. Importin-9 wraps around the core, globular region of H2A-H2B to form an extensive interface. The nature of this interface coupled with quantitative analysis of deletion mutants of H2A-H2B...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6453568/ https://ncbi.nlm.nih.gov/pubmed/30855230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43630 |
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