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Evidence for the nuclear import of histones H3.1 and H4 as monomers

Newly synthesised histones are thought to dimerise in the cytosol and undergo nuclear import in complex with histone chaperones. Here, we provide evidence that human H3.1 and H4 are imported into the nucleus as monomers. Using a tether‐and‐release system to study the import dynamics of newly synthes...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Apta‐Smith, Michael James, Hernandez‐Fernaud, Juan Ramon, Bowman, Andrew James
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166134/
https://ncbi.nlm.nih.gov/pubmed/30177573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798714
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