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Tertiary amine synthesis via reductive coupling of amides with Grignard reagents
A new iridium catalyzed reductive coupling reaction of Grignard reagents and tertiary amides affording functionalised tertiary amine products via an efficient and technically-simple one-pot, two-stage experimental protocol, is reported. The reaction – which can be carried out on gram-scale using as...
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| Publicat a: | Chem Sci |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5676097/ https://ncbi.nlm.nih.gov/pubmed/29163902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03613b |
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