General Pyrrolidine Synthesis via Iridium-Catalyzed Reductive Azomethine Ylide Generation from Tertiary Amides and Lactams

[Image: see text] An iridium-catalyzed reductive generation of both stabilized and unstabilized azomethine ylides and their application to functionalized pyrrolidine synthesis via [3 + 2] dipolar cycloaddition reactions is described. Proceeding under mild reaction conditions from both amide and lact...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Yamazaki, Ken, Gabriel, Pablo, Di Carmine, Graziano, Pedroni, Julia, Farizyan, Mirxan, Hamlin, Trevor A., Dixon, Darren J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291578/
https://ncbi.nlm.nih.gov/pubmed/34306810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.1c01589
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