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Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Sirtuin 2 (SIRT2) is a member of a family of NAD (+)‐dependent histone deacetylases (HDAC) that play diverse roles in cellular metabolism and especially for aging process. SIRT2 is located in the nucleus, cytoplasm, and mitochondria, is highly expressed in the central nervous system (CNS), and has b...
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| Publicat a: | Aging Cell |
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| Autors principals: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5676070/ https://ncbi.nlm.nih.gov/pubmed/28984064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12682 |
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