Antioxidants Halt Axonal Degeneration in a Mouse Model of X-Adrenoleukodystrophy

OBJECTIVE: Axonal degeneration is a main contributor to disability in progressive neurodegenerative diseases in which oxidative stress is often identified as a pathogenic factor. We aim to demonstrate that antioxidants are able to improve axonal degeneration and locomotor deficits in a mouse model o...

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Autors principals: López-Erauskin, Jone, Fourcade, Stéphane, Galino, Jorge, Ruiz, Montserrat, Schlüter, Agatha, Naudi, Alba, Jove, Mariona, Portero-Otin, Manuel, Pamplona, Reinald, Ferrer, Isidre, Pujol, Aurora
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229843/
https://ncbi.nlm.nih.gov/pubmed/21786300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22363
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