GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways

Available therapeutic options for advanced B cell precursor acute lymphoblastic leukemia (pre-B ALL) are limited. Many lead to neutropenia, leaving patients at risk of life-threatening infections and result in bad outcomes. New treatment options are needed to improve overall survival. We previously...

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Gepubliceerd in:Oncotarget
Hoofdauteurs: Ye, Wei, Jiang, Zhiwu, Lu, Xiaoyun, Ren, Xiaomei, Deng, Manman, Lin, Shouheng, Xiao, Yiren, Lin, Simiao, Wang, Suna, Li, Baiheng, Zheng, Yi, Lai, Peilong, Weng, Jianyu, Wu, Donghai, Ma, Yuguo, Chen, Xudong, Wen, Zhesheng, Chen, Yaoyu, Feng, Xiaoyan, Li, Yangqiu, Liu, Pentao, Du, Xin, Pei, Duanqing, Yao, Yao, Xu, Bing, Ding, Ke, Li, Peng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675611/
https://ncbi.nlm.nih.gov/pubmed/29152059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10881
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