Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia

Functional screening for compounds represents a major hurdle in the development of rational therapeutics for B-acute lymphoblastic leukemia (B-ALL). In addition, using cell lines as valid models for evaluating responses to novel drug therapies raises serious concerns, as cell lines are prone to geno...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Jiang, Zhiwu, Wu, Di, Ye, Wei, Weng, Jianyu, Lai, Peilong, Shi, Pengcheng, Guo, Xutao, Huang, Guohua, Deng, Qiuhua, Tang, Yanlai, Zhao, Hongyu, Cui, Shuzhong, Lin, Simiao, Wang, Suna, Li, Baiheng, Wu, Qiting, Li, Yangqiu, Liu, Pentao, Pei, Duanqing, Du, Xin, Yao, Yao, Li, Peng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739741/
https://ncbi.nlm.nih.gov/pubmed/29290956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22466
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