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Harnessing fungal nonribosomal cyclodepsipeptide synthetases for mechanistic insights and tailored engineering

Nonribosomal peptide synthetases represent potential platforms for the design and engineering of structurally complex peptides. While previous focus has been centred mainly on bacterial systems, fungal synthetases assembling drugs like the antifungal echinocandins, the antibacterial cephalosporins o...

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Dades bibliogràfiques
Publicat a:Chem Sci
Autors principals: Steiniger, Charlotte, Hoffmann, Sylvester, Mainz, Andi, Kaiser, Marcel, Voigt, Kerstin, Meyer, Vera, Süssmuth, Roderich D.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674221/
https://ncbi.nlm.nih.gov/pubmed/29163920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03093b
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