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Harnessing fungal nonribosomal cyclodepsipeptide synthetases for mechanistic insights and tailored engineering

Nonribosomal peptide synthetases represent potential platforms for the design and engineering of structurally complex peptides. While previous focus has been centred mainly on bacterial systems, fungal synthetases assembling drugs like the antifungal echinocandins, the antibacterial cephalosporins o...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Steiniger, Charlotte, Hoffmann, Sylvester, Mainz, Andi, Kaiser, Marcel, Voigt, Kerstin, Meyer, Vera, Süssmuth, Roderich D.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674221/
https://ncbi.nlm.nih.gov/pubmed/29163920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03093b
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