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Butyrate and propionate inhibit antigen-specific CD8(+) T cell activation by suppressing IL-12 production by antigen-presenting cells

Short chain fatty acids (SCFAs), such as acetate, butyrate and propionate, are products of microbial macronutrients fermentation that distribute systemically and are believed to modulate host immune responses. Recent data have indicated that certain SCFAs, such as butyrate and propionate, directly m...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Nastasi, Claudia, Fredholm, Simon, Willerslev-Olsen, Andreas, Hansen, Morten, Bonefeld, Charlotte Menné, Geisler, Carsten, Andersen, Mads Hald, Ødum, Niels, Woetmann, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673935/
https://ncbi.nlm.nih.gov/pubmed/29109552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15099-w
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