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Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4(+) T cells in cutaneous T-cell lymphoma

Staphylococcus aureus is implicated in disease progression in cutaneous T-cell lymphoma (CTCL). Here, we demonstrate that malignant T cell lines derived from CTCL patients as well as primary malignant CD4(+) T cells from Sézary syndrome patients are considerably more resistant to alpha-toxin-induced...

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Veröffentlicht in:Oncoimmunology
Hauptverfasser: Blümel, Edda, Willerslev-Olsen, Andreas, Gluud, Maria, Lindahl, Lise M., Fredholm, Simon, Nastasi, Claudia, Krejsgaard, Thorbjørn, Surewaard, Bas G. J., Koralov, Sergei B., Hu, Tengpeng, Persson, Jenny L., Bonefeld, Charlotte Menné, Geisler, Carsten, Iversen, Lars, Becker, Jürgen C., Andersen, Mads Hald, Woetmann, Anders, Buus, Terkild Brink, Ødum, Niels
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791457/
https://ncbi.nlm.nih.gov/pubmed/31646088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1641387
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