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Butyrate and propionate inhibit antigen-specific CD8(+) T cell activation by suppressing IL-12 production by antigen-presenting cells

Short chain fatty acids (SCFAs), such as acetate, butyrate and propionate, are products of microbial macronutrients fermentation that distribute systemically and are believed to modulate host immune responses. Recent data have indicated that certain SCFAs, such as butyrate and propionate, directly m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nastasi, Claudia, Fredholm, Simon, Willerslev-Olsen, Andreas, Hansen, Morten, Bonefeld, Charlotte Menné, Geisler, Carsten, Andersen, Mads Hald, Ødum, Niels, Woetmann, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673935/
https://ncbi.nlm.nih.gov/pubmed/29109552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15099-w
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