Butyrate and propionate inhibit antigen-specific CD8(+) T cell activation by suppressing IL-12 production by antigen-presenting cells

Short chain fatty acids (SCFAs), such as acetate, butyrate and propionate, are products of microbial macronutrients fermentation that distribute systemically and are believed to modulate host immune responses. Recent data have indicated that certain SCFAs, such as butyrate and propionate, directly m...

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Foilsithe in:Sci Rep
Main Authors: Nastasi, Claudia, Fredholm, Simon, Willerslev-Olsen, Andreas, Hansen, Morten, Bonefeld, Charlotte Menné, Geisler, Carsten, Andersen, Mads Hald, Ødum, Niels, Woetmann, Anders
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673935/
https://ncbi.nlm.nih.gov/pubmed/29109552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15099-w
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