Novel ATP‐competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells

Malignant pleural mesothelioma (MPM), an asbestos‐related occupational disease, is an aggressive and incurable tumor of the thoracic cavity. Despite recent advances in MPM treatment, overall survival of patients with MPM is very low. Recent studies have implicated that PI3K/Akt signaling is involved...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Yamaji, Masayuki, Ota, Akinobu, Wahiduzzaman, Md, Karnan, Sivasundaram, Hyodo, Toshinori, Konishi, Hiroyuki, Tsuzuki, Shinobu, Hosokawa, Yoshitaka, Haniuda, Masayuki
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673922/
https://ncbi.nlm.nih.gov/pubmed/28960945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1179
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