Novel ATP‐competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells

Malignant pleural mesothelioma (MPM), an asbestos‐related occupational disease, is an aggressive and incurable tumor of the thoracic cavity. Despite recent advances in MPM treatment, overall survival of patients with MPM is very low. Recent studies have implicated that PI3K/Akt signaling is involved...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Yamaji, Masayuki, Ota, Akinobu, Wahiduzzaman, Md, Karnan, Sivasundaram, Hyodo, Toshinori, Konishi, Hiroyuki, Tsuzuki, Shinobu, Hosokawa, Yoshitaka, Haniuda, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673922/
https://ncbi.nlm.nih.gov/pubmed/28960945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1179
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