Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells

Loss of heterozygosity or mutation of the family with sequence similarity 46, member C (FAM46C) gene on chromosome band 1p12 is associated with shorter overall survival of patients with multiple myeloma (MM). In this study, using human MM cell lines (KMS‐11, OCI‐My5, and ANBL‐6), we generated FAM46C...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kanasugi, Jo, Hanamura, Ichiro, Ota, Akinobu, Karnan, Sivasundaram, Lam, Vu Quang, Mizuno, Shohei, Wahiduzzaman, Md, Rahman, Md Lutfur, Hyodo, Toshinori, Konishi, Hiroyuki, Tsuzuki, Shinobu, Hosokawa, Yoshitaka, Takami, Akiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226186/
https://ncbi.nlm.nih.gov/pubmed/32176823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14386
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