A human bi-specific antibody against Zika virus with high therapeutic potential

Zika virus (ZIKV), a mosquito-borne flavivirus, causes devastating congenital birth defects. We isolated a human monoclonal antibody (mAb), ZKA190, that potently cross-neutralizes multi-lineage ZIKV strains. ZKA190 is highly effective in vivo in preventing morbidity and mortality of ZIKV-infected mi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell
Κύριοι συγγραφείς: Wang, Jiaqi, Bardelli, Marco, Espinosa, Diego A., Pedotti, Mattia, Ng, Thiam-Seng, Bianchi, Siro, Simonelli, Luca, Lim, Elisa X.Y., Foglierini, Mathilde, Zatta, Fabrizia, Jaconi, Stefano, Beltramello, Martina, Cameroni, Elisabetta, Fibriansah, Guntur, Shi, Jian, Barca, Taylor, Pagani, Isabel, Rubio, Alicia, Broccoli, Vania, Vicenzi, Elisa, Graham, Victoria, Pullan, Steven, Dowall, Stuart, Hewson, Roger, Jurt, Simon, Zerbe, Oliver, Stettler, Karin, Lanzavecchia, Antonio, Sallusto, Federica, Cavalli, Andrea, Harris, Eva, Lok, Shee-Mei, Varani, Luca, Corti, Davide
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2017
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673489/
https://ncbi.nlm.nih.gov/pubmed/28938115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.002
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