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A human bi-specific antibody against Zika virus with high therapeutic potential
Zika virus (ZIKV), a mosquito-borne flavivirus, causes devastating congenital birth defects. We isolated a human monoclonal antibody (mAb), ZKA190, that potently cross-neutralizes multi-lineage ZIKV strains. ZKA190 is highly effective in vivo in preventing morbidity and mortality of ZIKV-infected mi...
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Publicado no: | Cell |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673489/ https://ncbi.nlm.nih.gov/pubmed/28938115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.002 |
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