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Inhibition of PI3K/Akt/mTOR overcomes cisplatin resistance in the triple negative breast cancer cell line HCC38

BACKGROUND: Widely established targeted therapies directed at triple negative breast cancer (TNBC) are missing. Classical chemotherapy remains the systemic treatment option. Cisplatin has been tested in TNBC but bears the disadvantage of resistance development. The purpose of this study was to ident...

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Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Gohr, Katharina, Hamacher, Alexandra, Engelke, Laura H., Kassack, Matthias U.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670521/
https://ncbi.nlm.nih.gov/pubmed/29100507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3695-5
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