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RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway

Ovarian cancer remains the leading cause of death in gynecologic malignancies partially because of resistance to chemotherapy. In the present study, we show that RY-2f, a chemically synthesized isoflavone analog, inhibited ovarian cancer cell proliferation, blocked cell cycle in G2/M phase and induc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Liu, Mingming, Qi, Zihao, Liu, Bingzhi, Ren, Yi, Li, Hanbin, Yang, Gong, Zhang, Qian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694831/
https://ncbi.nlm.nih.gov/pubmed/26325371
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