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Disassembly/Reassembly Strategy for the Production of Highly Pure GroEL, a Tetradecameric Supramolecular Machine, Suitable for Quantitative NMR, EPR and Mutational Studies

GroEL, a prototypical member of the chaperonin class of chaperones, is a large supramocular machine that assists protein folding and plays an important role in proteostasis. GroEL comprises two heptameric rings, each of which encloses a large cavity that provides a folding chamber for protein substr...

Полное описание

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Библиографические подробности
Опубликовано в: :Protein Expr Purif
Главные авторы: Wälti, Marielle A., Clore, G. Marius
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669812/
https://ncbi.nlm.nih.gov/pubmed/28951283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2017.09.010
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