Tailored nanostructured platforms for boosting transcorneal permeation: Box–Behnken statistical optimization, comprehensive in vitro, ex vivo and in vivo characterization

Ocular drug delivery systems suffer from rapid drainage, intractable corneal permeation and short dosing intervals. Transcorneal drug permeation could increase the drug availability and efficiency in the aqueous humor. The aim of this study was to develop and optimize nanostructured formulations to...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Elsayed, Ibrahim, Sayed, Sinar
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669792/
https://ncbi.nlm.nih.gov/pubmed/29133980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S150366
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