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Lyophilized phytosomal nanocarriers as platforms for enhanced diosmin delivery: optimization and ex vivo permeation

Diosmin (DSN) is an outstanding phlebotonic flavonoid with a tolerable potential for the treatment of colon and hepatocellular carcinoma. Being highly insoluble, DSN bioavailability suffers from high inter-subject variation due to variable degrees of permeation. This work endeavored to develop novel...

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Détails bibliographiques
Auteurs principaux: Freag, May S, Elnaggar, Yosra SR, Abdallah, Ossama Y
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704438/
https://ncbi.nlm.nih.gov/pubmed/23861584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S45231
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