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Optimization, ex vivo permeation, and stability study of lipid nanocarrier loaded gelatin capsules for treatment of intermittent claudication

In this study, an optimized nanodispersible oral dosage form (containing a lactate ester) was developed for cilostazol (CZL). CZL is a phosphodiesterase inhibitor used for intermittent claudication. We aimed to improve the dissolution rate and absorption of CZL giving it a better chance of oral bioa...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Sallam, Marwa Ahmed, Marín Boscá, María Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508069/
https://ncbi.nlm.nih.gov/pubmed/26203244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S83123
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