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C-Terminal Truncated α-Synuclein Fibrils Contain Strongly Twisted β-Sheets

[Image: see text] C-terminal truncations of monomeric wild-type alpha-synuclein (henceforth WT-αS) have been shown to enhance the formation of amyloid aggregates both in vivo and in vitro and have been associated with accelerated progression of Parkinson’s disease (PD). The correlation with PD may n...

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Xehetasun bibliografikoak
Argitaratua izan da:J Am Chem Soc
Egile Nagusiak: Iyer, Aditya, Roeters, Steven J., Kogan, Vladimir, Woutersen, Sander, Claessens, Mireille M. A. E, Subramaniam, Vinod
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2017
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668890/
https://ncbi.nlm.nih.gov/pubmed/28968082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07403
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