Deletion of UCP1 enhances ex vivo aortic vasomotor function in female but not male mice despite similar susceptibility to metabolic dysfunction

Females are typically more insulin sensitive than males, which may be partly attributed to greater brown adipose tissue (BAT) activity and uncoupling protein 1 (UCP1) content. Accordingly, we tested the hypothesis that UCP1 deletion would abolish sex differences in insulin sensitivity and that white...

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Publicado en:Am J Physiol Endocrinol Metab
Autores principales: Winn, Nathan C., Grunewald, Zachary I., Gastecki, Michelle L., Woodford, Makenzie L., Welly, Rebecca J., Clookey, Stephanie L., Ball, James R., Gaines, T’Keaya L., Karasseva, Natalia G., Kanaley, Jill A., Sacks, Harold S., Vieira-Potter, Victoria J., Padilla, Jaume
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668596/
https://ncbi.nlm.nih.gov/pubmed/28655717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00096.2017
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