Deletion of UCP1 enhances ex vivo aortic vasomotor function in female but not male mice despite similar susceptibility to metabolic dysfunction

Females are typically more insulin sensitive than males, which may be partly attributed to greater brown adipose tissue (BAT) activity and uncoupling protein 1 (UCP1) content. Accordingly, we tested the hypothesis that UCP1 deletion would abolish sex differences in insulin sensitivity and that white...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Winn, Nathan C., Grunewald, Zachary I., Gastecki, Michelle L., Woodford, Makenzie L., Welly, Rebecca J., Clookey, Stephanie L., Ball, James R., Gaines, T’Keaya L., Karasseva, Natalia G., Kanaley, Jill A., Sacks, Harold S., Vieira-Potter, Victoria J., Padilla, Jaume
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668596/
https://ncbi.nlm.nih.gov/pubmed/28655717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00096.2017
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