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Loss of UCP1 exacerbates Western diet-induced glycemic dysregulation independent of changes in body weight in female mice
We tested the hypothesis that female mice null for uncoupling protein 1 (UCP1) would have increased susceptibility to Western diet-induced “whitening” of brown adipose tissue (AT) and glucose intolerance. Six-week-old C57BL/6J wild-type (WT) and UCP1 knockout (UCP1(−/−)) mice, housed at 25°C, were r...
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| Wydane w: | Am J Physiol Regul Integr Comp Physiol |
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| Główni autorzy: | , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Physiological Society
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283932/ https://ncbi.nlm.nih.gov/pubmed/27881400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00425.2016 |
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