Loss of UCP1 exacerbates Western diet-induced glycemic dysregulation independent of changes in body weight in female mice

We tested the hypothesis that female mice null for uncoupling protein 1 (UCP1) would have increased susceptibility to Western diet-induced “whitening” of brown adipose tissue (AT) and glucose intolerance. Six-week-old C57BL/6J wild-type (WT) and UCP1 knockout (UCP1(−/−)) mice, housed at 25°C, were r...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Winn, Nathan C., Vieira-Potter, Victoria J., Gastecki, Michelle L., Welly, Rebecca J., Scroggins, Rebecca J., Zidon, Terese M., Gaines, T’Keaya L., Woodford, Makenzie L., Karasseva, Natalia G., Kanaley, Jill A., Sacks, Harold S., Padilla, Jaume
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283932/
https://ncbi.nlm.nih.gov/pubmed/27881400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00425.2016
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