Deletion of UCP1 enhances ex vivo aortic vasomotor function in female but not male mice despite similar susceptibility to metabolic dysfunction

Females are typically more insulin sensitive than males, which may be partly attributed to greater brown adipose tissue (BAT) activity and uncoupling protein 1 (UCP1) content. Accordingly, we tested the hypothesis that UCP1 deletion would abolish sex differences in insulin sensitivity and that white...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Winn, Nathan C., Grunewald, Zachary I., Gastecki, Michelle L., Woodford, Makenzie L., Welly, Rebecca J., Clookey, Stephanie L., Ball, James R., Gaines, T’Keaya L., Karasseva, Natalia G., Kanaley, Jill A., Sacks, Harold S., Vieira-Potter, Victoria J., Padilla, Jaume
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668596/
https://ncbi.nlm.nih.gov/pubmed/28655717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00096.2017
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